The drug Dapsone 100 MG / Pyrimethamine 12.5 MG Oral Tablet (105337) is listed as precribable in RxNORM but further investigation does call into question if this drug combination is available in the US. The use of this drug combination in the test patients should be reviewed At this time we are only able to update value sets annually. CMS/ONC/NLM are looking into the impact of more frequent updates to value sets but do not anticipate review of this code until the next annual update.

CMS 52v2 contains a value set called Dapsone and pyrimethamine. Value set is 2.16. 840.1.113883.3.464.1003.196.12.1202. The value set contains a single RXNORM code 105337 which is not in our current Medispan database. After review, it appears this drug is no longer available in North America as it was deemed no longer effective. This drug is being included in the Cypress test patients and should not be.