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CMS 996 - Clarification on Adverse Reaction to Thrombolytic Medications

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      The Thrombolytic Medication value set includes tenecteplase and reteplase, but there is not a type equivalent to these medications in the Adverse reaction to Thrombolytics value set. Is the intent that tenecteplase and reteplase should align with "Alteplase" in the Adverse reaction to Thombolytics value set? 

      Adverse reaction to thrombolytics    OID: 2.16.840.1.113762.1.4.1170.6 includes the following codes:

      293571007    Streptokinase adverse reaction (disorder)    SNOMEDCT    2021-09    2.16.840.1.113883.6.96
      293572000    Urokinase adverse reaction (disorder)            SNOMEDCT    2021-09    2.16.840.1.113883.6.96
      293573005    Alteplase adverse reaction (disorder)            SNOMEDCT    2021-09    2.16.840.1.113883.6.96
      293574004    Anistreplase adverse reaction (disorder)    SNOMEDCT    2021-09    2.16.840.1.113883.6.96

      Thrombolytic medications             OID: 2.16.840.1.113762.1.4.1170.4 includes the following codes:

      10106    streptokinase    RXNORM    2022-01    2.16.840.1.113883.6.88
      11055    urokinase    RXNORM    2022-01    2.16.840.1.113883.6.88
      259280    tenecteplase    RXNORM    2022-01    2.16.840.1.113883.6.88
      40028    anistreplase    RXNORM    2022-01    2.16.840.1.113883.6.88
      76895    reteplase    RXNORM    2022-01    2.16.840.1.113883.6.88
      8410    alteplase    RXNORM    2022-01    2.16.840.1.113883.6.88

       

       UNION "Adverse Effect to Thrombolytic Medications Before End of ED Encounter"

             "ED Encounter with STEMI Diagnosis" EDwSTEMI
                WITH ["Adverse Event": "Thrombolytic medications"] ThrombolyticAdverseEvent
                  SUCH THAT ThrombolyticAdverseEvent.type in "Adverse reaction to thrombolytics"
                    AND ThrombolyticAdverseEvent.relevantDatetime before 
                      end of EDwSTEMI.relevantPeriod

            maraas Michael Araas
            bh030380 Brandi Bencun
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