Thank you for your question regarding CMS104 Discharged on Antithrombotic Therapy. This measure uses the value set Antithrombotic Therapy for Ischemic Stroke 2.16.840.1.113762.1.4.1110.62. You can reference the applicable codes containing these value sets on the Value Set Authority Center (VSAC) at https://vsac.nlm.nih.gov/ . Click on the “Search Value Sets” tab and enter the value set ID to review codes included in the respective value set. This grouping value set consists of RxNorm concepts that represent a dose formulation to meet intent and are designed to broadly to meet various clinical scenarios. This value set does include several variations of Aspirin 81 and your local medications codes should be mapped to one of the RXNORM codes within the value set. The medication value sets developed for the program contain RxNorm codes that are Semantic Clinical Drugs (SCD), generic, and prescribeable. Semantic Clinical Drug (SCD) codes and are generalizable drug concepts. Each RxNorm clinical drug name reflects the active ingredients, strengths, and dose form comprising that drug. Your local medication codes need to be mapped to the SCD RxNorm codes found in the value set in order to satisfy the electronic clinical quality measure. We are unable to provide specific guidance related to the mapping of codes. We recommend you consult with your EHR vendor and clinical partners. If mapping is conducted, you should maintain documentation in case of a CMS audit. If there are relevant updates to RXNORM we will consider adjustments to the value sets for the next Annual Update. These are the 81 mg aspirin codes found in the latest version: -1722689 aspirin 81 MG / calcium carbonate 777 MG Oral Tablet -1811631 aspirin 81 MG / omeprazole 40 MG Delayed Release Oral Tablet -318272 aspirin 81 MG Chewable Tablet -308416 aspirin 81 MG Delayed Release Oral Tablet -252857 aspirin 81 MG Oral Capsule -243670 aspirin 81 MG Oral Tablet You can find more information about this in the eCQM Logic and Implementation Guidance located here: https://ecqi.healthit.gov/sites/default/files/eCQM-Logic-and-Guidance-v6.pdf in the section titled "Drug Representations Used in Value Sets".