Thank you for your question regarding CMS506v6: Safe Use of Opioids - Concurrent Prescribing. Patients who left against medical advice are currently included in the measure. For reference, the denominator exclusions for this measure include the following: patients have cancer that begins prior to or during the encounter or are ordered or are receiving palliative or hospice care (including comfort measures, terminal care, and dying care) during the hospitalization or in an emergency department encounter or observation stay immediately prior to hospitalization, patients discharged to another inpatient care facility, and patients who expire during the inpatient stay.