Thank you for your inquiry specific to CMS819v2 (Hospital Harm – Opioid-Related Adverse Event). The Numerator for the measure is inpatient hospitalizations where an opioid antagonist was administered outside of the operating room and within 12 hours following administration of an opioid medication. Your understanding of the intent is correct; opioid antagonists that are administered in the operating room are excluded from the evaluation for the Numerator. In your scenario the Numerator is met because the opioid antagonist (via IV route) was administered outside of the operating room and was within 12 hours following the 9/3/2023 9:00am administration of the opioid medication.