Thank you for your inquiry regarding CMS2v11: Preventive Care and Screening: Screening for Depression and Follow-Up Plan. Per the measure specifications, the depression screening is required once per measurement period, not at all encounters; and it is not limited to the first encounter during the measurement period. If a patient has multiple depression screenings during the measurement period, the measure assesses the most recent depression screening completed either during the qualifying encounter or within the 14 days prior to that encounter.