Adventist Health System
Office of Clinical Effectiveness
Hospital Harm – Opioid-Related Adverse Events

This measure has high sensitivity and high specificity and we support development of this measure with suggested items to improve harm identification.
For naloxone administered > 24 hours after admission, consider requiring documentation of opioid administration prior to naloxone. This will increase the measure accuracy to capture opioid-related harms requiring naloxone as naloxone may also be administered for reasons such as unresponsiveness in the absence of an opioid.
Consider capturing additional opioid-related harms for the same patient by establishing a time interval during which another administration of Naloxone would not re-fire for the same event. If the Nalaxone is administered again and is associated with a new dose or new narcotic, it should be captured as a separate harm.