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1. It correlates with patient research unique identifiers supplied in the request with data-site-specific identifiers for each intended data site and it identifies four sites that store relevant data sets.
2. The Coordinating Center System adds technical criteria corresponding to the approved data set to be supplied by each site.
3. It submits separate requests to each of four data sites.
• Each data site receives a list of patients using the site local identifier and returns the matching set of records defined in the Data the Data Use Agreement.
4. The Coordinating Center System processes the responses (success/failure) and the data returned from each data site and returns the data sets to Advanced Research Institute system (Research Information System)

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